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PICO (participants, intervention/exposure, comparison, outcomes, and study design) criteria for inclusion and exclusion of studies After excluding duplicate studies, two authors (AH and MP) independently reviewed articles based on titles, abstracts, or full-texts to identify relevant studies. Additionally, the reference lists of related review articles and the retrieved studies were also hand-searched to detect eligible trials that might have been missed. The search keywords were seldom based on vinegar and related phrases to minimize the chance of missing studies which reported lipids or glycemic related markers as secondary outcomes. Therefore, in the current study, we performed a systematic review and meta-analysis of all published clinical trials to provide a more precise estimation of the effects of ACV on serum lipid parameters and glycemic markers in adults. 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Former Florida State University football player Travis Rudolph kisses his mother, Linda Rudolph, while speaking to media after a jury acquitted him of all charges in a fatal shooting in 2021, Wednesday, June 7, 2023, outside the Palm Beach County Courthouse in West Palm Beach, Fla. (Andres Leiva/The Palm Beach Post via AP) Former Florida State University football player Travis Rudolph after a prayer circle during a prayer circle with family and friends while awaiting the jury’s verdict in his murder trial, Wednesday, June 7, 2023, in the Palm Beach County Courthouse in downtown West Palm Beach, Fla. Former Florida State football player Travis Rudolph reacts after a jury acquitted him of all charges in a fatal shooting in 2021, Wednesday, June 7, 2023, in the Palm Beach County Courthouse in downtown West Palm Beach, Fla. 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